The quickest way to do that is to end the War on Drugs, which hasn't accomplished anything, except to make a lot of bad people very rich. Legalize and regulate drug sales, so they have to meet Truth-in-labeling laws. Take all the money we're wasting on drug law enforcement, and put it into treatment programs and drug education. Hire a small staff to review federal drug-related convictions, with the goal of eventually identifying about 10 a week for pardons.
Let the tobacco farmers grow industrial hemp instead of tobacco, and reduce their dependence on getting people hooked on nicotine.
A modest proposal to help win the war on drugs.